Incidence of coagulase-negative staphylococcal bacteremia among ICU patients: decontamination studies as a natural experiment

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Increasing Incidence Of Coagulase - Negative Staphylococcal Sepsis - An Emerging Challenges

IntroductionCoagulase negative Staphylococcus (CoNS), being a part of the commensal flora, have long remained neglected as mere contaminants till their recently reported increased rate of isolation, evidenced their potential as nosocomial pathogens. Treatment is difficult due to confusion in pathogenecity and multi-drug resistance. Aim of the study was to to identify the different species of Co...

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Clinical Characteristics of Methicillin-resistant Coagulase-negative Staphylococcal Bacteremia in a Tertiary Hospital

Objective Coagulase-negative staphylococci are among the most frequently isolated microorganisms in blood cultures. The aim of this study was to assess [1] the clinical characteristics of methicillin-resistant, coagulase-negative staphylococci bacteremia and [2] the susceptibility of the isolated bacteria to glycopeptides. Methods We retrospectively reviewed the medical records of 70 patients f...

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Management of the catheter in documented catheter-related coagulase-negative staphylococcal bacteremia: remove or retain?

BACKGROUND Studies and guidelines recommending the retention of the central venous catheter (CVC) in patients with coagulase-negative staphylococcal bacteremia were based on loose definitions of bacteremia and/or did not evaluate the risk of recurrence. In this study, we used strict definitions of coagulase-negative staphylococcal bacteremia to determine the impact of CVC retention on response ...

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Use of rifampin in persistent coagulase negative staphylococcal bacteremia in neonates

BACKGROUND Coagulase negative staphylococci (CoNS) are the most common cause of neonatal sepsis in the Neonatal Intensive Care Unit (NICU). A minority of neonates does not respond to vancomycin therapy and develops persistent bacteremia, which may be treated with rifampin. We evaluated the use of rifampin in persistent CoNS bacteremia. METHODS Retrospective study of 137 neonates with CoNS bac...

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ICU stay promotes enrichment and dissemination of multiresistant coagulase-negative staphylococcal strains.

Patients in the intensive care unit (ICU) are prone to be colonized and infected by multi-resistant bacteria. It is previously known that nosocomial infections are often preceded by cross-transmission events. The aim of the present investigation was to study the impact of the patient's length of ICU stay on the resistance patterns, diversity and dissemination of coagulase-negative staphylococci...

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ژورنال

عنوان ژورنال: European Journal of Clinical Microbiology & Infectious Diseases

سال: 2019

ISSN: 0934-9723,1435-4373

DOI: 10.1007/s10096-019-03763-0